Book Reviews
December 1942

Neural Mechanisms in Poliomyelitis.

Author Affiliations

By Howard A. Howe and David Bodian. Price $3.50. Pp. 234, with 39 illustrations. New York: The Commonwealth Fund, 1942.

Am J Dis Child. 1942;64(6):1127-1128. doi:10.1001/archpedi.1942.02010120167015

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This volume is of great interest, especially to any one who has worked with poliomyelitis. It is in reality a compilation of a series of investigations by the authors, most of which have been previously published. They have to do with problems in neural anatomy and related subjects and are somewhat technical in character. Nevertheless, it is necessary for persons who are interested in poliomyelitis to understand the fundamental bases of pathology and to know the groundwork of virus behavior and how the biologic processes of the nervous system are affected by it. The authors considered neurotropism and poliomyelitis virus, the role of neurons in its dissemination, its behavior in the peripheral nerves and in non-neural tissue, the pathologic reaction, the virus-refractory state of nerve cells, the problems of immunity in poliomyelitis and second attacks. The results of their studies point to the alimentary tract as the portal of entry

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