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Case Reports
February 1943


Author Affiliations


Am J Dis Child. 1943;65(2):314-319. doi:10.1001/archpedi.1943.02010140122009

Rickets in infants is one of the most common diseases found in pediatric practice. However, active rickets after 2 years of age is uncommon, and only a few cases have been reported of its occurrence in older children, who have been extremely resistant to treatment and required massive doses of vitamin D before cure was accomplished. Three such cases have been reported by Albright, Butler and Bloomberg,1 Eliot and Park2 and Bakwin, Bodansky and Schorr.3

It is now generally agreed that there is a secondary hyperplasia of the parathyroid glands in rickets, with increase in the secretion of the hormone.4 Albright spoke of "the importance of the parathyroid hormone in maintaining a relatively normal serum calcium concentration in cases of rickets, in which a deficiency and limited absorption of the calcium occur." He also expressed the belief "that the low phosphorus level in rickets is dependent

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