There is hardly anything to be found in the pediatric literature on the subject of the folds and creases of the skin, their appearance and disappearance, their character and their relations to other changes of the body. This omission is striking, since these folds and creases belong among the peculiarities which make the body of the infant and the child appear different from the body of the adult and which, on the other hand, have always been known to laymen and physicians, to painters and sculptors. But they seem to have escaped the attention of physicians, and it is only occasionally that observations are encountered concerning them in descriptions or characterizations of patients. Since these features may contribute to the diagnosis of morbid conditions and to the differentiation of stages of development, they may also contain some value for the practicing physician, especially the pediatrician.
The general content of this
NASSAU E. FOLDS AND CREASES OF THE SKIN DURING CHILDHOOD. Am J Dis Child. 1943;66(6):615-623. doi:10.1001/archpedi.1943.02010240020005