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Progress in Pediatrics
February 1944


Am J Dis Child. 1944;67(2):139-143. doi:10.1001/archpedi.1944.02020020053008

The multiplicity of theories regarding the causes of recurrent and chronic diarrhea in infancy and childhood reflected the poor understanding of the subject until Andersen,1 by differentiation of cystic fibrosis of the pancreas from the other syndromes given the name of celiac disease, stimulated attempts at reclassification.

While there is still no unanimity of opinion as to the relationships of these syndromes, sufficient facts are now available to justify an attempt at classification. In the outline which follows I have in the main adopted Andersen's classification, and I shall discuss each of the groups listed below and describe cases illustrative of each type of metabolic diarrhea.


  1. Diarrhea due to overfeeding and grossly improper feeding.

  2. Parenteral diarrhea, due to gastrointestinal manifestations of systemic infections.

  3. Infectious and toxic diarrhea and the vague gastrointestinal intoxications.

  4. Mechanical diarrhea.

  5. "Metabolic" diarrhea, the celiac syndrome.

    • Cystic fibrosis of

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