This report is based on a study of cases of gastric and duodenal ulcers encountered at the Babies Hospital from 1930 to 1944; it includes a presentation of the case of a 12 year old boy who was operated on for duodenal ulceration with obstruction. The age group covered is from birth to 12 years.
Although peptic ulcer is rarely demonstrated in infancy and childhood, it probably occurs with greater frequency than is reported. Of the 8,260 cases of peptic ulcer listed in the records of the Mayo Clinic from 1906 to 1924 Proctor1 found only 2 involving children. However, he emphasized the fact that the history of ulcer often dates back to childhood, when the condition existed unrecognized.
Duodenal ulcer is more common than gastric ulcer, the ratio varying from 2:1 to 6:1 in different reports.
Ulceration has been reported to occur in utero. It probably accounts for
DONOVAN EJ, SANTULLI TV. GASTRIC AND DUODENAL ULCERS IN INFANCY AND IN CHILDHOOD. Am J Dis Child. 1945;69(3):176-179. doi:10.1001/archpedi.1945.02020150037007