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May 1946

NEW TYPE OF FAMILIAL CONGENITAL CHRONIC HEMOLYTIC ANEMIA

Author Affiliations

MANILA, PHILIPPINE ISLANDS
From the Department of Pediatrics, College of Medicine, University of the Philippines.

Am J Dis Child. 1946;71(5):492-505. doi:10.1001/archpedi.1946.02020280037005
Abstract

IN the year 1940 we submitted a paper on chronic familial hemolytic anemia to the Acta Medica Philippina for publication. Unfortunately, no new issues could appear after the war started in the Far East. In 1945, when the Americans liberated the Philippine Islands, the office of the Acta was burned and the editor killed. In the year 1942, we published a paper1 on erythroblastic anemia following splenectomy in cases of chronic familial hemolytic anemia. We described 2 observed cases in which erythroblastosis developed after splenectomy. In the following years we studied this response to splenectomy thoroughly and were able to establish facts which prove that we are dealing with a definite clinical entity not described until now. There are cases of so-called atypical hemolytic anemias in the literature. Our cases, however, do not at all correspond to these cases. We are aware that our observations are still incomplete, and

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