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To the Editor:—I have just read the article on mumps by Dr. Alwin C. Rambar which appeared in the January 1946 issue of the American Journal of Diseases of Children. I should like to inform you of my own observations concerning the treatment of that disease and of its terrible complication, orchitis.
From the inception of the disease I treat adults and adolescents with a sulfonamide drug, sulfapyridine (2-[paraaminobenzenesulfonamido]-pyridine, Soludagenan 693, prepared by the firm Specia Rhône Poulenc, Paris). I inject 1 Gm. of the drug intramuscularly both morning and evening. All the usual complications, such as orchitis, ovaritis, meningoencephalitis and rheumatism, have completely disappeared from my practice.
However, when I have to treat a patient suffering from orchitis I give an intramuscular injection of 1 Gm. of Soludagenan three times a day, and in serious cases I give an intravenous injection morning and evening of 0.5 to 1
PAYCHÉRE A. MUMPS: USE OF CONVALESCENT SERUM IN THE TREATMENT AND PROPHYLAXIS OF ORCHITIS. Am J Dis Child. 1946;72(6):761. doi:10.1001/archpedi.1946.02020350128011