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To the Editor:—Doctor Paychère's results in reducing the incidence of orchitis in adolescents and adults to zero are most interesting, although they are different from my own and from those of Haerem and others.
I have used sulfonamide compounds in the treatment of mumps orchitis, although the records of these patients are not now available. My recollection, however, is definitely that no noticeable benefit resulted. I doubt that the use of sulfonamide drugs parenterally would have produced results any different from those obtained by oral administration.
There are several reports in the literature of the use of the sulfonamide compounds in the treatment and prevention of orchitis. Haerem, in the Military Surgeon92:306-312, March 1943, treated 500 patients with mumps, dividing his groups so that 100 were controls, 100 each were treated with sulfathiazole, sulfapyridine and sulfanilamide, and 100 were given convalescent serum. His conclusions were that the
RAMBAR AC. MUMPS: USE OF CONVALESCENT SERUM IN THE TREATMENT AND PROPHYLAXIS OF ORCHITIS. Am J Dis Child. 1946;72(6):761. doi:10.1001/archpedi.1946.02020350128012