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This book, written by the director of the Wallace Research Laboratory, is the result of ten years' continuous research on the subject. It contains the records of 300 patients of all ages who were examined, and of many more who were observed, during the ten year period. Through the performance of 50 autopsies, it was possible to study every aspect of the disease from birth to death, the occurrence of which ranged from the age of 2 days to over 30 years. These data are contained in the opening chapters on "Physical Characteristics," "Mental Development," "Nervous System," "Endocrine Pathology," "General Pathology," "Growth and Development of the Skull and Bones," "X-Ray Studies" and "Hematology and Biochemistry."
These observations offer an amount of material which is far greater than that to which those studying the condition have hitherto had access, and the author has done full justice to the subject in his
Mongolism and Cretinism: A Study of the Clinical Manifestations and the General Pathology of Pituitary and Thyroid Deficiency.. Am J Dis Child. 1947;74(2):250. doi:10.1001/archpedi.1947.02030010258012