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November 1947

TOTAL AND FRACTIONAL BLOOD LIPID LEVELS IN DISEASES OF CHILDHOOD

Am J Dis Child. 1947;74(5):563-575. doi:10.1001/archpedi.1947.02030010577002
Abstract

THE LITERATURE contains a number of studies concerned with abnormalities of the blood lipids in various childhood diseases. However, with rare exception these studies do not take into account the entire blood lipid complex. Recent advances in the physiology of normal lipid metabolism emphasize the need for information with regard to the levels of all the blood lipids and such ratios as may exist among them.

The following report presents the total and fractional plasma lipid levels in 50 children with diseases which are classified diagnostically in table 1. Systematic investigation of changes produced by these diseases in the complete blood lipid pattern is the point of emphasis in this study.

PROCEDURE  Postabsorptive total and fractional plasma lipid levels were obtained in 50 children with the diseases indicated in table 1. The technics of Bloor1 for the fractionation and the differential analysis of plasma lipids were employed. The following

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