RECENTLY, 3 cases of systemic aleukemic nonlipid reticuloendotheliosis were studied by us. The similarity of clinical course, and especially of the cutaneous lesions, prompted us to report them and to review the literature briefly.
The occurrence of reticuloendothelial disturbances has been known for many years.1 Letterer2 described a special type of reticuloendotheliosis in a young child almost twenty-five years ago. Nevertheless, relatively few of these cases have been reported.3
REPORT OF CASES
Case 1.4—A 5 month old white girl was admitted to the New York Post-Graduate Hospital on Aug. 13, 1946. The chief complaints included infected eczema, poor gain in weight, moderate diarrhea and drainage from both ears. She was a second child, weight at birth was 8 pounds 3 ounces (3,714 Gm.). There was no pertinent family history. Soon after birth papular, pustular and pyodermic lesions had been noted on the body and scalp.
VARGA C, RICHTER MN, DeSANCTIS AG. SYSTEMIC ALEUKEMIC RETICULOENDOTHELIOSIS (LETTERER-SIWE DISEASE). Am J Dis Child. 1948;75(3):376-384. doi:10.1001/archpedi.1948.02030020388008