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Case Reports
January 1950


Author Affiliations

From the Department of Pediatrics, New York University-Bellevue Medical Center, University Hospital (formerly New York Post-Graduate Hospital).

Am J Dis Child. 1950;79(1):105-110. doi:10.1001/archpedi.1950.04040010115013

SEVERAL cases of the syndrome of infantile cortical hyperostosis have been reported since Caffey and Silverman1 first described this heretofore unknown disease of infants. Smyth, Potter and Silverman2 were among the early workers to add to the rapidly growing number of cases. These were followed with reports by Whipple,3 Dickson and his associates,4 Shuman5 and Gipson and Clark6 and from the Children's Hospital, Washington, D. C.7 The purpose of this report is to present 2 additional cases of this syndrome and to discuss some variable aspects of the disease.

REPORT OF CASES  Case 1.—M. A. F., a 5 month old Italian infant, was admitted to the babies' wards of the New York Post-Graduate Hospital on Nov. 11, 1947 because of a facial swelling since 2 weeks of age.Family History.—The parents were living and in good health. There were no known familial

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