By Max-Henri Béguin. Supplement to Annales pædiatrici; Jahrbuch für Kinderheilkunde, fasc. 49. Price, 8 Swiss francs. Pp. 96, with 14 illustrations. S. Karger, Holbeinstrasse 22, Basel, Switzerland, 1949.
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This monograph comes from the Clinique Infantile Universitaire (Hospital Jenner), Berne, Switzerland. The author reports on 35 cases of tuberculosis in infants and children treated with streptomycin alone or with streptomycin and paraaminosalicylic acid ("aminacyl"). The patients are divided into groups according to the type of tuberculosis present. Before giving his own cases in detail, the author reviews the literature on other similar patients treated with streptomycin. In this way one arrives with him, through the experiences cited, at a considered opinion of the optimum dosage and of the best methods of administration. In the 12 patients with tuberculous meningitis, no difference in response was noted between those receiving streptomycin alone and those receiving it in association with a sulfonamide drug or paraaminosalicylic acid. All showed pronounced and prolonged amelioration of symptoms but a final fatal outcome, except in 1 child. In this patient there was complete recovery; however, tubercle
La streptomycine et le "Pas" dans le traitement de la tuberculose chez l'enfant.. AMA Am J Dis Child. 1950;80(6):1054-1055. doi:10.1001/archpedi.1950.04040021069025