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January 1911

INFLUENZAL MENINGITIS AND ITS EXPERIMENTAL PRODUCTION

Author Affiliations

NEW YORK
From the laboratories of the Babies' Hospital and of the Rockefeller Institute.

Am J Dis Child. 1911;I(1):42-58. doi:10.1001/archpedi.1911.04100010045005
Abstract

The extension of the practice of employing lumbar puncture as an aid to the diagnosis of meningitis has had, as one effect, the establishment of the important fact that the influenza bacillus is a not infrequent cause of sero-purulent meningitis. That the influenza bacillus may act as a cause of acute inflammation of the meninges has been known since the publication of Pfuhl's1 illustrative cases in 1892, but that it acts as a not infrequent cause of that condition we are just beginning to learn. Influenzal meningitis appears to be a very severe and highly fatal form of meningitis and to be exceeded in respect to its fatality only by the pneumococcus and tuberculous forms. It remains, however, for the present, an undecided question whether influenza bacilli may not occur in the cerebrospinal fluid without setting up inflammation, just as pneumococci and some other organisms have been known to

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