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The value of transfusion in infants has been demonstrated in the treatment of hemorrhagic disease of the new-born and in cases of hemorrhage after injuries or operations. That this procedure has not been more frequently and successfully tried in these conditions is probably due to the technical difficulties of the operation in infants, and especially in the new-born infant. The chief difficulty is found in uniting the artery of the donor to the small and inaccessible vein of the infant. The largest superficial veins of a baby's arm are so small that one must resort to the less accessible veins of the thigh which, at the best, are scarcely large enough. However, when once a satisfactory connection is made between artery and vein, a flow of comparatively short duration is sufficient to transfer enough blood for an infant. In a baby weighing 8 pounds, a flow of five minutes corresponds
VINCENT B. BLOOD TRANSFUSION IN INFANTS BY MEANS OF GLASS TUBES. Am J Dis Child. 1911;I(5):376-381. doi:10.1001/archpedi.1911.04100050057005