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July 1911

A PREPARATORY STUDY OF THE BACILLUS ACIDOPHILUS IN REGARD TO ITS POSSIBLE THERAPEUTIC USE

Am J Dis Child. 1911;II(1):30-38. doi:10.1001/archpedi.1911.04100070037004
Abstract

The recent advances in our knowledge of the biology of the gastroenteric tract have been so great that it seems time to begin a study of the practical use which can be made of individual organisms. Prominent among these organisms in the intestine is the obligate member of the acidoduric group, the Bacillus acidophilus.

It is to be noted in a general way that (1) this bacillus is a carbohydrate saprophyte; (2) it does not produce toxins; (3) it is a fermental organism, by fermental meaning an organism capable of breaking up the carbohydrates; (4) its habitat is the large intestine; (5) it thrives on carbohydrates, especially the sugars, such as dextrose, lactose and maltose; (6) it produces relatively large amounts of lactic acid from fermentable sugars; (7) it is antagonistic to the proteolytic organisms producing putrefaction, provided sugar is present; (8) although it produces acid it grows best when

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