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October 1911

RELATIONSHIP OF GASTRIC TO PANCREATIC FAT DIGESTION IN INFANTS

Author Affiliations

MINNEAPOLIS
From the Laboratory of Physiological Chemistry, University of Minnesota.

Am J Dis Child. 1911;II(4):243-247. doi:10.1001/archpedi.1911.04100100024002
Abstract

The presence of a ferment in the adult stomach, which has the power of splitting neutral fat into its component fatty acids and glycerin, the gastric lipase, has been confirmed by recent studies.

Although Marcet,1 Cash,2 Ogata3 and Vaughan Harley4 found fatty acids in the stomach contents, it remained for Volhard5 to demonstrate the presence of fat-splitting ferment and bring the subject forward for study. Stade,6 one of Volhard's pupils, confirmed his results and suggested the technic of examination which goes by his name.

Inouye7 failed to find evidence of a gastric lipase, but Falloise8 confirmed its presence, and Laquer found the secretion from a Pawlow small stomach to be active in splitting fat, thus proving that the activity cannot be due to regurgitated pancreatic steapsin. Stef. v. Pesthy8 confirmed the fact that fat is split in the stomach.

The study

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