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October 1911

HIPPURIC ACID IN THE URINE OF NORMAL BREAST-FEED INFANTS

Author Affiliations

BALTIMORE
From the Department of Pediatrics and the Department of Pharmacology, Johns Hopkins University.

Am J Dis Child. 1911;II(4):248-251. doi:10.1001/archpedi.1911.04100100029003
Abstract

The urine of the normal breast-fed infant is mainly distinguished by negative characteristics. This is a statement made by Mayerhofer1 in his recent paper. In this paper attention is called to the absence of such substances as glycuronic acid, indican, urobilin, etc., in the urine of these individuals. According to the same author some of the products normally encountered in the urine of adults, like the substances paired with glycocoll, namely, benzoic acid, etc., have not been made the subject of detailed investigation. With regard to the occurrence of hippuric acid in the urine of infants, only a few scanty references came to our notice. Marchand2 as well as Meissner and Shephard3 state that the occurrence of hippuric acid in the infant's urine is a well-known fact. Amberg and Morrill,4 examining 260 c.c. of a mixed urine obtained from several healthy breast-fed infants, were unable to

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