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January 1912

SPLENOMEGALY (GAUCHER)

Am J Dis Child. 1912;III(1):28-40. doi:10.1001/archpedi.1912.04100130035004
Abstract

It is the object of this paper to report the history of a family, several members of which suffer from a type of splenic enlargement usually desiginated as that of Gaucher, and to make a critical study of all the reported cases of this disease, with the hope of proving that although these cases resemble other diseases, yet closer study gives overwhelming proof that they must be classed by themselves as an entirely distinct and separate disease. The diseases from which it is especially to be differentiated are splenic anemia in adults and von Jaksch's disease in infants. Under the term "splenic anemia," Osler includes all those cases of idiopathic enlargement of the spleen associated with anemia, which were formerly classified as splenic pseudoleukemia, anemia splenica, lymph adénie splénique and splenic form of Hodgkin's disease. He states: "I purposely have not spoken of anemia with enlarged spleen in very young

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