In 1906 I reported the results of an investigation of certain clinical aspects of rheumatic fever in childhood, which was based on a series of 300 consecutive patients admitted to the wards of the Children's Hospital. Of these 300 patients, 209 were discharged from the hospital with signs of organic valvular disease of the heart. The after history of these cases appeared to me to be a point of great interest, with a practical value bearing directly on the question of prognosis, and on certain aspects of treatment. I determined at the time to keep in communication as far as possible, with all of these discharged patients, and at the same time the scope of the investigation was extended beyond the limit of cardiac disease of rheumatic origin, by including all other patients of cardiac disease admitted to the hospital during the period from which the original series was taken.
DUNN CH. CARDIAC DISEASE IN CHILDHOOD, WITH SPECIAL REFERENCE TO PROGNOSIS. Am J Dis Child. 1913;VI(2):104-116. doi:10.1001/archpedi.1913.04100320041006