One of the great disadvantages in the study of the digestive disturbances of infancy is our inability to determine quickly the quantity of fat present in an infant's stool. Qualitative tests, while of value, do not suffice, for under normal conditions we may encounter neutral fat, free fatty acids and soaps in an infant's stool. Our requirements will not be fulfilled until we have some approximate method for determining the neutral fats, free fatty acids and the soaps as they exist in the stool when it leaves the body, or, in other words, as they exist in the intestine uninfluenced by external agencies.
In pursuance of this need we began last September to study the various methods now in use for the estimation of fat in stools with the hope that we might find a way of shortening some of the existing methods, or of combining the different principles involved
COWIE DM, HUBBARD WS. A RAPID CLINICAL METHOD FOR THE ESTIMATION OF TOTAL FAT IN INFANTS' STOOLS. Am J Dis Child. 1913;VI(3):192-198. doi:10.1001/archpedi.1913.04100330050007