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August 1914

THE PRESENCE OF LACTIC ACID IN THE URINE IN CYCLIC VOMITING OF CHILDHOOD

Author Affiliations

NEW HAVEN, CONN.
From the Sheffield Laboratory of Physiological Chemistry, Yale University, New Haven, Conn.

Am J Dis Child. 1914;VIII(2):127-129. doi:10.1001/archpedi.1914.04300010133003
Abstract

Although the etiology of recurrent or periodic vomiting of children has been attributed to a variety of abnormal conditions none of the numerous theories advanced offers an adequate explanation for the cause of the symptoms observed.1 The more recent ideas tend to correlate recurrent vomiting with some defects in metabolic processes, notably those concerned with carbohydrate transformations. Thus, in the pathologic state under discussion, diacetic acid and acetone in the urine are particularly prominent as abnormal constituents of that excretion. Inasmuch as carbohydrate deficiency in inanition in childhood leads rapidly to the same urinary findings, one may query with a great deal of pertinence whether these compounds mentioned can be regarded as factors in the etiology of cyclic vomiting, for they may indicate merely the effect of withdrawal of food, especially carbohydrates.

The purpose of the present communication is to report a case of cyclic vomiting showing one feature

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