The fact that children have not been supposed to be very susceptible to typhoid fever, and, when affected, are apt to exhibit an irregular type of the disease, would seem to render a study of cases of value for future comparison and reference. It is during an epidemic that they are most liable to be attacked, so that such an occasion affords the most favorable opportunity for a study of any peculiarities the disease may show in early life. Since the employment of Widal's test, the field has widened by proving that typhoid fever in certain mild types may be overlooked in children or mistaken for some other affection.
During the fall of 1913, an epidemic of typhoid fever occurred in the lower East side of New York, including 521 reported cases, with a mortality of 11.7 per cent. Many children were attacked as shown by the following reported number
CHAPIN HD. A CLINICAL STUDY OF TYPHOID FEVER IN CHILDREN. Am J Dis Child. 1914;VIII(2):130–133. doi:10.1001/archpedi.1914.04300010136004