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November 1914


Am J Dis Child. 1914;VIII(5):336-356. doi:10.1001/archpedi.1914.04300010345003

I have already1 reported a case of splenomegaly Gaucher in a child 4 years old. In March, 1912, splenectomy was performed on this patient. The child did not survive the operation. Histologic study of the liver, the spleen, the lymph glands and the bone-marrow confirmed the diagnosis previously made on a clinical basis. This is the first case to be reported in the English language in which the diagnosis in a child was made prior to operation or to necropsy, and was confirmed later. The diagnosis was correctly made in a child only once before, by De Jong and Van Heukelom in 1909.

In the previous paper a study of this disease was presented as it occurs both in adults and in children. In this paper only the cases which occurred in infants and children will be discussed. Although the clinical picture is almost identical with that which occurs

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