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September 1915

DOES THE BACILLUS ABORTUS (BANG) INFECT MAN?

Author Affiliations

NEW YORK
From the Division of Laboratories, Department of Health, New York.

Am J Dis Child. 1915;X(3):203-205. doi:10.1001/archpedi.1915.04110030052007
Abstract

The frequent presence in milk of Bacillus abortus, the causative agent of contagious abortion of cattle and its pathogenicity for, or at least its ability to cause abortion in, many species of animals, raises the question whether it may not be infectious for man. Mohler and Traum1 tested the serum of forty-two persons by the agglutination and complement-fixation reaction with negative results. Fifty-six adenoids and tonsils from milk-consuming children were injected into guinea-pigs. The material from one case produced nodular areas in the liver, but cultures remained sterile. The injection of tonsils from another patient produced typical lesions in guinea-pigs and B. abortus was isolated. More recently Larson and Sedgwick2 presented further evidence of the possible infection of man. They found that some women giving a history of abortion gave a positive complement-fixation reaction using B. abortus as antigen. They also examined the blood of 425 children, and

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