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April 2013

Neonatal Lung Function and Later Respiratory Consequences

Author Affiliations

Author Affiliations: Department of Paediatric Respiratory Medicine, Oslo University Hospital, Rikshospitalet; Institute of Clinical Medicine, University of Oslo; and Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.

JAMA Pediatr. 2013;167(4):394-395. doi:10.1001/jamapediatrics.2013.119

As the twig is bent, the tree inclines (perhaps).—Benjamin Burrows and Lynn M. Taussig1

The title of the article by Burrows and Taussig written in 1980 could also be used to designate the article by Mullane and colleagues2 in the present issue of JAMA Pediatrics. The title relates to the observation that early reductions in lung function have a long-lasting effect on respiratory health and lung function later in life. Mullane and colleagues2 present the results from an 18-year follow-up of a birth cohort recruited in Perth, Western Australia, during the late 1980s. This birth cohort established by Mullane and colleagues together with the birth cohort established in Tucson, Arizona, by Stern and colleagues3 were the first cohorts of young children recruited at birth and followed up with respect to asthma and allergic diseases. The Tucson study previously presented results from a 22-year follow-up.3 These long-term follow-up birth cohorts have inspired other research groups and provided important new knowledge.

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