Until recently, duodenal ulcers have been considered rare in infancy and childhood. Since 1908, groups of cases have been published by several writers, and the increasing number of reports during the past three years indicates that the condition is not a very uncommon one. and that it has been probably overlooked in the past.
In the literature I have found references or full reports of ninety-one cases of duodenal ulcer in the first year of life, making, with four cases of my own reported in this paper, ninety-five cases for study. All but twenty-one of these have been published since 1908. These facts indicate how little this condition was known until five years ago. In the post mortem records of the Babies' Hospital embracing 1,800 autopsies, fully 90 per cent. of which were in children under 1 year, duodenal ulcer is recorded but four times, and, curiously, three of these
HOLT LE. DUODENAL ULCERS IN INFANCY. Am J Dis Child. 1913;VI(6):381-393. doi:10.1001/archpedi.1913.04100360002001