[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.211.247.249. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
July 1926

CHEMICAL CHANGES IN THE BODY OCCURRING AS THE RESULT OF VOMITING

Author Affiliations

ST. LOUIS
From the Department of Pediatrics, Washington University School of Medicine, and the St. Louis Children's Hospital.

Am J Dis Child. 1926;32(1):1-28. doi:10.1001/archpedi.1926.04130070008001
Abstract

Although considerable attention has been given to the occurrence and significance of acidosis, it is only recently that changes of body neutrality to the alkaline side have received much notice.1

REVIEW OF THE LITERATURE  Wilson and his co-workers2 were among the first to consider alkalosis as a possible cause of tetany. They found, following parathyroidectomy, that there was a slight increase in the pH or alkalinity of the blood, a change in the hemoglobin dissociation curve and a rise in alveolar carbon dioxide tension. Accompanying these changes there was found also an increase in urinary pH (alkalinity) with diminished ammonia and acid excretion. It was further assumed that with the onset of tetany, the acid products of muscular contraction were sufficient to change this primary increased alkalinity to a normal or more acid reaction.In 1918, McCann3 reported chemical analyses of the blood following parathyroidectomy,

×