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Comment & Response
September 2014

Multiple Nutrient Intake Recommendations Guide Dietary Supplement Formulations

Author Affiliations
  • 1DSM Nutritional Products, Parsippany, New Jersey
JAMA Pediatr. 2014;168(9):863-864. doi:10.1001/jamapediatrics.2014.426

To the Editor We read the study in JAMA Pediatrics by Madden et al1 with great interest. However, it is apparent that the authors were either unaware of federal regulations regarding dietary supplement labeling or chose to ignore them.

There are 2 sets of nutrient intake reference values that dietary supplement manufacturers and consumers must consider. First are the values put forth by the Institute of Medicine (IOM), which include the recommended dietary allowance (RDA) and adequate intake (AI) values.2 Second, the Food and Drug Administration (FDA) has established intake standards for micronutrients, namely reference daily intakes (RDIs). The RDIs are used to derive the percent daily value (% DV), which manufacturers are required by law to disclose on products.3,4 Although similar, the RDIs are not identical to the IOM values and can sometimes exceed the recommended dietary allowance (or AI) by a substantial margin.

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