[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 2,297
Citations 0
July 2015

Long-term Follow-up of Placental Transfusion in Full-term Infants

Author Affiliations
  • 1Academic Department of Paediatrics, Brighton and Sussex Medical School and University Hospitals, Brighton, England
  • 2College of Nursing, University of Rhode Island, Kingston
JAMA Pediatr. 2015;169(7):623-624. doi:10.1001/jamapediatrics.2015.0431

The effects of redistributing placental blood into healthy full-term newborns at birth by delayed umbilical cord clamping (CC) have been demonstrated in many studies.1 The short-term benefits include higher hemoglobin concentration after birth and increased iron stores until 6 months of age. Early clamping of the cord was introduced in the past to avoid maternal hemorrhage without considering potential neonatal adverse effects. A meta-analysis by McDonald et al1 found no significant differences in postpartum hemorrhage rates when comparing early vs late CC groups in 5 trials that included 2260 women. When that Cochrane review was published, only 1 clinical trial had reported any data on long-term neurodevelopmental outcomes of full-term newborns. Previously, Andersson and colleagues2 reported the outcomes of 4-month-old infants who were randomized to early vs late CC. They did not report any significant difference in scores using the Ages and Stages Questionnaire.

First Page Preview View Large
First page PDF preview
First page PDF preview