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To the Editor I read with great interest the article by Stratakis et al1 in JAMA Pediatrics. In a large pooled analysis of 15 population-based birth cohorts in Europe and the United States, Stratakis et al1 found that high maternal fish consumption (>3 times/week) during pregnancy was associated with increased risk of rapid growth in infancy and childhood overweight/obesity at ages 4 years and 6 years. These findings were in line with the US Food and Drug Administration and Environmental Protection Agency’s updated advice on fish consumption for pregnant women. However, it is noteworthy that the US Food and Drug Administration and Environmental Protection Agency’s advice was mainly based on consideration of mercury contamination in fish. While prenatal mercury exposure is well known to adversely affect child neurodevelopment, it has a neutral effect on obesity development.2
Bao W. Fish Intake During Pregnancy and Offspring Adiposity. JAMA Pediatr. 2016;170(8):808-809. doi:10.1001/jamapediatrics.2016.1026