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JAMA Pediatrics Clinical Challenge
September 2016

Newborn With a Diffuse Rash

Author Affiliations
  • 1University of Virginia, Charlottesville
JAMA Pediatr. 2016;170(9):903-904. doi:10.1001/jamapediatrics.2015.4602

A 1-day-old male infant in the neonatal intensive care unit was evaluated for a diffuse rash present at delivery. The patient was born at full term via spontaneous vaginal delivery after an uncomplicated pregnancy with APGAR scores of 8 and 9 at 1 and 5 minutes, respectively. His mother was varicella nonimmune and had no active rashes including in the perineal area. Physical examination of the patient revealed widespread papulovesicular, crusted lesions on the arms, legs, face, scalp, and trunk (Figure 1). The palms, soles, and oral mucosa were spared. The patient was afebrile.

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