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Corticosteroids and Kawasaki disease (KD) have had a complicated relationship. Sentiment has fluctuated between the extremes, from indispensable to proscribed, even as the roles of intravenous immunoglobulin (IVIG) and aspirin have been defined. As the meta-analysis by Chen et al1 in this issue of JAMA Pediatrics demonstrates, the findings of recent studies are finally lending some clarity to when steroids can be beneficial in KD.
Sundel R. Clarifying the Role of Corticosteroids in Kawasaki Disease. JAMA Pediatr. Published online October 17, 2016. doi:10.1001/jamapediatrics.2016.2307