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Comment & Response
May 1, 2017

Treatment of Opioid Use Disorder During Pregnancy and Cases of Neonatal Abstinence Syndrome

Author Affiliations
  • 1Department of Pediatrics, Boston Medical Center, Boston, Massachusetts
  • 2Division of Neonatology, Vanderbilt University School of Medicine; Nashville, Tennessee
JAMA Pediatr. Published online May 1, 2017. doi:10.1001/jamapediatrics.2017.0854

To the Editor During the last 2 decades, use of prescription opioids and heroin increased throughout the United States. As use of licit and illicit opioids grew among pregnant women, cases of neonatal abstinence syndrome (NAS) surged nearly 5-fold nationwide.1 In their article, Brown et al2 described the rapid rise of NAS diagnoses in Kentucky from 2008 to 2014, growing at a rate twice the national mean. The authors raised the concern that state and federal public health interventions implemented to combat opioid use disorder during the study period may not have been effective, given that rates of NAS did not decrease.

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