It would be inappropriate to use our data to support the hypothesis Dr Hertz advocates, namely, that in the first week of life there is no statistically significant difference in levels of physiologic jaundice between infants given standard infant formula and those who are breastfeeding effectively. As we indicated in our article,1 many studies show that breast-fed infants have significantly more jaundice than formula-fed infants during the first week of life. Our study comparing jaundice in infants fed human milk vs formula shows P values of .10, .08, and .06 at age 5, 6, and 7 days, respectively. This strongly suggests that these 2 dietary groups might be significantly different with a larger sample size. There are no data in Dr Hertz's second reference2 to support the hypothesis she advocates.
Gourley GR, Kreamer B, Kosorok M. Nutrition and Jaundice: Hold the Bottle, Keep the Breast—Reply. Arch Pediatr Adolesc Med. 1999;153(9):1002-1003. doi: