Recently, Elliott et al1 examined a gastroschisis case series from 2 Reno, Nevada, hospitals, comparing patients with controls who had maternal birth dates within 1 year and who received prenatal care at the same clinics. Notable findings focused on patients with gastroschisis who had greater exposure to vasoconstrictive recreational drugs, including methamphetamine, prior to pregnancy. We raise several methodological concerns.
Kirby RS, Marshall J. Hospital-Based Clusters and the Epidemiology of Gastroschisis. Arch Pediatr Adolesc Med. 2010;164(6):583–584. doi:10.1001/archpediatrics.2010.79