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The Pediatric Forum
July 5, 2010

Analysis of Metformin Treatment for Adolescent Obesity at 48 Rather Than 24 Weeks After Treatment Cessation—Reply

Author Affiliations

Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2010

Arch Pediatr Adolesc Med. 2010;164(7):678-679. doi:10.1001/archpediatrics.2010.111

In reply

Both the conception of the study by the investigators and its subsequent selection by the Glaser Pediatric Research Network in 2001 were driven by the publication of a series of small, uncontrolled trials of metformin in obesity and/or insulin-resistant adolescents. We agree that lifestyle inventions for obese adolescents are important and thus designed our trial such that both metformin and placebo groups received the identical lifestyle intervention.

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