I read with interest the article titled "The Efficacy of Duct Tape vs Cryotherapy in the Treatment of Verruca Vulgaris."1 I have found, through years of experience, that the most efficient program for wart removal must include curettage of the wart, ie, removal of the outside layer to the point of a few drops of blood followed by the application of liquid nitrogen for a minimum of 30 to 45 seconds. A significant blister will then form. This will extricate the root of the wart, which is necessary for successful and permanent wart removal.A follow-up is required within 1 week. At this point, additional curettage and application of liquid nitrogen will result in at least a 75% cure, ie, removal of the entire wart and creation of a very small crater. Very large warts or plantar warts may require a third application. A third application will almost always result in permanent elimination of the wart.
Engel JJ. Effective Wart Removal. Arch Pediatr Adolesc Med. 2003;157(5):490–491. doi:10.1001/archpedi.157.5.490-a