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The Pediatric Forum
September 2003

Reducing the Error in Pediatrics Dosing

Arch Pediatr Adolesc Med. 2003;157(9):934. doi:10.1001/archpedi.157.9.934-a

I read the article by Amit and colleagues1 with great interest. I would like to address a practical issue related to this. Different drug companies produce different strengths of liquid formulations of the same drug. For example, some drug companies use 50 mg of cefixime/5 mL and a few use 100 mg/5 mL. Physicians have to remember which formulation has which quantity of the given drug per milliliter. It is difficult to remember the strength of each brand. Drug companies make such changes to show that they are unique, but it confuses the mind of the prescribing physician. Is it possible to standardize drug concentrations, such as requiring that all antibiotic solutions contain 125 mg of the drug per 5 mL? Such a requirement would reduce many of the errors in pediatrics prescriptions.

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