Copyright 2005 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2005
The study by Laslo-Baker et al1 reports poorer performance on some specific neurocognitive and behavioral outcomes among children whose mothers reported solvent exposures during pregnancy. However, the authors do not discuss important limitations of this study that preclude reaching cause-and-effect conclusions, specifically, the small size and questionable representativeness of the study populations, the limitations of the exposure assessment, the potential for both uncontrolled and residual confounding, and multiple comparisons with selective presentation of results.
Yarborough CM, Erdreich L. Child Neurocognitive and Behavioral Outcomes and Maternal Solvent Exposure During Pregnancy. Arch Pediatr Adolesc Med. 2005;159(7):690-692. doi:10.1001/archpedi.159.7.690-a