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IN INFANTS parenchymal diseases of the kidneys other than those associated with congenital anomalies, pyelonephritis and tumors are regarded as rarities. In this age group glomerulonephritis is uncommon and renal disease of vascular origin is virtually unknown. The experience in our laboratory over the last 10 years indicates, however, that a variety of major injuries to the renal parenchyma, based on vascular disturbances, occur in infants with sufficient frequency to warrant attention.Between 1940 and 1950 there were 40 cases of major renal disease associated with vascular dysfunction seen among 2,058 autopsies performed on infants and children in this department. This group does not include cases of renal infarct or focal embolic glomerulonephritis secondary to bacterial endocarditis. Of the 40 patients, 34 were infants. In the same 10 year period 18 patients with acute or chronic glomerulonephritis were studied at autopsy, and only two of these were under 2
ZUELZER WW, CHARLES S, KURNETZ R, NEWTON WA, FALLON R. CIRCULATORY DISEASES OF THE KIDNEYS IN INFANCY AND CHILDHOOD. AMA Am J Dis Child. 1951;81(1):1–2. doi:10.1001/archpedi.1951.02040030008001