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The second edition of this book has been revised so far as new approach is concerned, especially in regard to the relationship of mongolism to maternal condition. Here the author presents new facts to substantiate his opinion that mongolism develops in the fetus under a constellation of adverse factors which operate in the maternal organism and deprive the growing fetus of proper nutritional environment. He expresses his belief that studies of latent hypothryoidism, hypogonadism and hypopituitarism may reveal the condition prenatally.
The chapter on principles of treatment has been thoroughly revised. The author outlines his principles of treatment with thyroid, pituitary extract and other hormones, glutamic acid and education. He states that "under present conditions, treatment cannot restore full intelligence; the results of careful treatment carried out over several years lie between normal and the level usually reached by untreated patients."
The book is well written and excellently printed and
Mongolism and Cretinism. AMA Am J Dis Child. 1951;81(5):750-751. doi:10.1001/archpedi.1951.02040030763025