July 1952

Contribución al estudio del rabdomioblastoma.

Author Affiliations

By Ramiro Alvarez Zamora. Price, 50 pesetas. Pp. 82, with 18 illustrations. Librería De Ciencias Médicas, Barcelona, Spain, 1950.

AMA Am J Dis Child. 1952;84(1):139-140. doi:10.1001/archpedi.1952.02050010155021

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In this very excellent monograph on rhabdomyoblastoma the author has analyzed 72 cases from the medical literature and added 3 of his own. These "mixed tumor" sarcomas appear in the first two years of life on the anterior wall of the vagina. Their growth is continuous toward the exterior, and in time they metastasize into the softer surrounding tissues. They cause urinary difficulties that lead to hydronephrosis.

A new approach has been made by the author in histological differentiation of these cells as immature striated muscular elements. The prognosis is bad unless early treatment by extirpation of the tumor and adjacent tissue is made, with further radium treatment. Of all the known cases, in only three did the patients survive after 15 years of observation.

Although written in Spanish, this monograph is very easily understood, as the diagrams and plates are excellent. The bibliography is well chosen. This is a

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