THE COMBINATION of a short P-R interval and a prolonged QRS duration on the electrocardiogram in frequent association with attacks of paroxysmal tachycardia was first recognized as a syndrome in 1930 by Wolff, Parkinson, and White.1 Since that time several hundred cases have been reported. Most of the patients in these cases have been young adult males in good health except for the episodes of tachycardia.
Although the syndrome is not rare in the younger age group, the reported instances of this condition in infants and children to the age of 14 years are few.2
They are summarized in the table. Five additional cases, not reported in detail, were encountered in a study by Nadas and co-workers3 of 41 infants and children seen during a 20-year period because of paroxysmal tachycardia. One probable example in a 4½-year-old boy was described by Ziegler.4 Of the 26 patients
ENGLE MA. WOLFF-PARKINSON-WHITE SYNDROME IN INFANTS AND CHILDREN. AMA Am J Dis Child. 1952;84(6):692-705. doi:10.1001/archpedi.1952.02050060030002