February 1954

Physiological Changes in Plasma Proteins Characteristic of Human Reproduction: Cross-Sectional and Longitudinal Electrophoretic Data for Women During and Following Uncomplicated and Complicated Pregnancies.

Author Affiliations

By Icie G. Macy, Ph.D., Sc.D., and Harold C. Mack, M.D. Pp. 170, with tables and figures. Gratis to workers in either field. Children's Fund of Michigan, 660 Fredericks St., Detroit 2, 1952.

AMA Am J Dis Child. 1954;87(2):259. doi:10.1001/archpedi.1954.02050090247032

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This volume is an excellent presentation of the use of the Tiselius apparatus in the electrophoretic determination of the various protein fragments in the blood plasma. As such, its value probably will be in the relative rather than the absolute. The apparatus is complicated, and more than ordinary skill is required in its successful use. The subjects and methods of study are succinctly set forth with the advantages and disadvantages of the procedure. This method will undoubtedly prove to be a valuable tool in the search for more precise data of the physiologic variability of the plasma proteins. It is very possible that only very general evaluation can be made of the electrophoretic determinations as shown in this volume and large numbers of comparable figures will be necessary. This volume of 170 pages closes with 120 pages of seriatim data obtained by electrophoresis of the blood plasma proteins in pregnancy

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