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Article
October 1954

PIEBALDNESS, OF FAMILIAL WHITE SKIN SPOTTING (PARTIAL ALBINISM)

Author Affiliations

OMAHA
From the Department of Pediatrics, University of Nebraska College of Medicine and Children's Memorial Hospital.

AMA Am J Dis Child. 1954;88(4):481-484. doi:10.1001/archpedi.1954.02050100483008
Abstract

PIEBALDNESS, or familial white skin spotting, is a congenital defect of skin pigmentation which is of rare occurrence, inherited as a dominant characteristic. It is characterized by a defect in skin pigment which may involve the central portion of the brow, including a small portion of the scalp, with a resulting white forelock, areas on the anterior surface of chest, abdomen, and extremities, but with no involvement of the remainder of the face or back. The skin defects remain throughout life and are constant. The brow defect is usually triangular or diamond-shaped, and the eyebrows may be involved with white hairs. The depigmented areas of the extremities are usually bilateral, although not symmetrical, and may show much variety in extent and shape with clearly demarcated skin lines. The extremities and trunk may show small islands of normal pigmented skin within the depigmented area, varying in size from a few millimeters

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