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December 1954


Author Affiliations

From the Department of Pediatrics (Dr. O'Connor and Dr. McKey) and the Department of Pathology (Dr. Smith), Kern General Hospital.

AMA Am J Dis Child. 1954;88(6):740-742. doi:10.1001/archpedi.1954.02050100742005

REFERENCES to congenital leukemia are few in number.* Bernhard, Gore, and Kilby,9 in reviewing the literature in 1951, found 14 acceptable cases and added 4 of their own. In 1952, Casilli, Rumsey, and Satulsky10 reported a case of myeloblastic leukemia in the neonatal period. The criteria for acceptance as a case of congenital leukemia are not too clearly defined, but the presence of leukemia cells in the peripheral blood, bone marrow, and visceral organs of an infant in the neonatal period is highly suggestive. It is the purpose of this paper to report a case of congenital leukemia in a 5-day-old boy, with septicemia as a terminal event.

REPORT OF CASE  The infant was born at this hospital after a labor of approximately four hours. The mother was an Rh-positive 19-year-old woman, unipara and secundagravida, whose Kline and Kahn reactions were negative. Total length of pregnancy was estimated

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