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This book is based on a study of over 1,000 Mongols, traced from 1925 to 1949, of which 526 were alive, from Seeland and neighboring islands in Denmark. Its object is the study of the etiology and pathogenesis of Mongolism on the basis of a large unselected series of patients and throwing light on these problems through clinical and genealogical investigations.
The author has done this in an excellent manner. All details have been included of the patients' past history and physical examinations. Many photographs have been included. Physical features are discussed with the mental. X-ray and laboratory studies have been done, and a review is given of pathoanatomical investigations reported in the literature. Oster concludes that Mongolism is not a hereditary disease, but probably has its cause in exogenous factors related to the mother's depressed reproductive faculty.
This is the largest series of cases with which the reviewer is
Mongolism.. AMA Am J Dis Child. 1955;89(1):124. doi:10.1001/archpedi.1955.02050110140022