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"The treatment of the nephrosis syndrome is always a field of therapy in which the intelligence, the experience and the tenacity of the physician are found of the greatest use." Thus Imperato concludes this treatise on nephrosis with especial emphasis on its treatment.
Twelve cases of nephrosis in children 2 to 12 years of age are presented in detail; each child has been the subject of prolonged hospital study; many therapeutic procedures were tried. Including three more recent cases, he is able to report clinical cures in nine, improvement in five, and no change in one. The urinary findings and electrophoresis tests on the sera of seven of these nine were also normal. In these seven, the duration of the cure was at the time of the writing from 9 to 26 months.
The overcoming of the hypoproteinemia is regarded as the primary function of his recommended therapy. A high-protein
La Terapia della nefrosi nel bambino.. AMA Am J Dis Child. 1955;90(2):249. doi:10.1001/archpedi.1955.04030010251024