During the past several years many clinical investigators focused their attentions on the measurement of bodily functions and compartments. Several methods for the measurement of the body's fluid compartments and electrolyte content have been developed and evaluated. These have been greatly facilitated by the application of isotopic tracer techniques. Values for the volumes of body compartments and their electrolyte contents have been established and the influence of various diseases on these moieties have been documented. Data on the total body water and electrolyte content of the newborn infant, however, have been somewhat limited.
This study was undertaken to measure the total body water and exchangeable sodium in newborn infants. The current report presents the data obtained by measuring the total body water and exchangeable sodium simultaneously in a series of normal newborn infants.
Subjects and Methods
Studies were made on 17 newborn infants ranging in age from 6 hours to
CHRISTIAN JR, TALSO PJ, KARAZERIS MP, SPAFFORD NR, JACKSON H, LARSON M. Total Body Water and Exchangeable Sodium in Normal Full-Term Newborn Infants. AMA Am J Dis Child. 1956;92(4):325–329. doi:10.1001/archpedi.1956.02060030319001